Pathogenesis of scarlet fever, bacteremia, and toxic shock syndrome. Anti-M-1(+) = the presence of antibody to M protein type 1; Anti-M-1(−) = the absence of antibody to M protein type 1; Anti-SPEA(+) = antibody to SPEA; Anti-SPEA(−) = no antibody to SPEA; DIC = disseminated intravascular coagulation; M-1 + SPEA + = a group A streptococci strain that contains M protein type 1 and SPEA; SPEA = streptococcal pyrogenic exotoxin A. | Chuang, Y., Huang, Y. & Lin, T. Toxic Shock Syndrome in Children. Pediatr-Drugs 7, 11–24 (2005). https://doi.org/10.2165/00148581-200507010-00002

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