Partial/complete disappearance of parietal cells leading to impairment of hydrochloric acid and intrinsic factor production.
Atrophic gastritis. Helicobacter pylori–associated chronic active gastritis (Genta stain, 20x). Multiple organisms (brown) are observed adhering to gastric surface epithelial cells. A mononuclear lymphoplasmacytic and polymorphonuclear cell infiltrate is observed in the mucosa. | Chronic Inflammation Of. (2020) Atrophic Gastritis: Background, Pathophysiology, Etiology. Retrieved January 14, 2020, from https://emedicine.medscape.com/article/176036-overview
Atrophic gastritis. Intestinal metaplasia of the gastric mucosa (Genta stain, 20x). Intestinal-type epithelium with numerous goblet cells (stained blue with the Alcian blue stain) replace the gastric mucosa and represent gastric atrophy. Mild chronic inflammation is observed in the lamina propria. This pattern of atrophy is observed both in Helicobacter pylori–associated atrophic gastritis and autoimmune gastritis. | Chronic Inflammation Of. (2020) Atrophic Gastritis: Background, Pathophysiology, Etiology. Retrieved January 14, 2020, from https://emedicine.medscape.com/article/176036-overview
Clinical features
Clinical manifestations of chronic atrophic gastritis (CAG) | Rodriguez-Castro, K. I., Franceschi, M., Noto, A., Miraglia, C., Nouvenne, A., Leandro, G., … Di Mario, F. (2018). Clinical manifestations of chronic atrophic gastritis. Acta Bio-Medica : Atenei Parmensis, 89(8-S), 88–92. https://doi.org/10.23750/abm.v89i8-S.7921
