Hemolytic anemia

Group of disorders characterized by a premature RBC destruction that exceeds the compensatory capacity of the bone marrow to increase RBC production and keep up with the loss.

Monoclonal gammopathy of undetermined significance (MGUS)

Premalignant, clonal plasma cell disorder, characterized by the presence of a monoclonal (M) protein, <10% clonal plasma cells in the bone marrow, and absence of multiple myeloma or related lymphoplasmacytic malignancies (LPMs).

Plasma cell dyscrasias (PCDs)

Spectrum of progressively more severe monoclonal gammopathies characterized by the expansion of a population of monoclonal bone-marrow plasma cells that produce monoclonal immunoglobulins.


Condition with life-threatening potential in which diminution of the oxygen-carrying capacity of circulating hemoglobin occurs due to conversion of some or all of the four iron species from the reduced ferrous [Fe2+] state to the oxidized ferric [Fe3+] state.