Ocular System

Calcific band keratopathy

Degenerative condition of the cornea, characterised by deposition of grey-white opacities in the superficial corneal layers, most commonly in the exposed inter-palpebral region.

  • Composed of fine dust-like calcium deposits in the sub-epithelium, Bowman’s layer and the anterior stroma.

Clinical features

  • Decreased vision
  • Foreign body sensation
  • Ocular irritation
  • Redness (occasionally)
  • Photophobia
  • Visible cosmetic changes to the eye
Causes of band keratopathy. Clinical picture demonstrating range of clinical presentations of band keratopathy. (a) Peripheral, not visually significant; (b) Central, mild visual symptoms; (c): Dense central band, visually significant; (d) Prominent in a blind eye causing ocular surface discomfort/pain. | Al-Hity, A., Ramaesh, K., & Lockington, D. (2018). EDTA chelation for symptomatic band keratopathy: results and recurrence. Eye (London, England), 32(1), 26–31.


  • EDTA chelation (DOC)
  • Phototherapeutic keratectomy (refractive cases)

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