Ocular System

Corneal dystrophy (CD)

Collection of rare hereditary non-inflammatory disorders of abnormal deposition of substances in the cornea.


International Classification of Corneal Dystrophies (IC3D) (2015):

Sub-classified by the anatomic location affected
  • Epithelial/subepithelial CD:
    • Epithelial basement membrane corneal dystrophy (EBMCD), aka map-finger-dot dystrophy, Cogan microcystic dystrophy, and anterior basement membrane dystrophy
    • Meesmann corneal dystrophy (MECD) or juvenile epithelial corneal dystrophy
  • Epithelial-stromal or Bowman’s CD:
    • Reis-Bückler’s corneal dystrophy (RBCD)
    • Thiel-Behnke corneal dystrophy (honeycomb dystrophy)
  • Stromal CD:
    • Macular corneal dystrophy (MCD)  
    • Granular corneal dystrophy (GCD)
    • Lattice corneal dystrophy (LCD)
  • Endothelial CD:
    • Fuchs endothelial corneal dystrophy (FECD)  
    • Posterior polymorphous corneal dystrophy (PPCD)  
    • Congenital hereditary endothelial dystrophy (CHED)  
    • X-linked endothelial corneal dystrophy (XECD) 

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