Febrile reaction induced by a drug without additional clinical features like skin eruption.
- M/C occurs after 7-10 days of drug administration, persists as long as the drug is continued, disappears soon after stopping the drug, and will rapidly reappear if the drug is restarted.
- Agents most commonly associated:
- Penicillins, cephalosporins, antituberculars, quinidine, procainamide, methyldopa, and phenytoin.