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Internal Medicine

Diabetic Foot Syndrome

The presence of several characteristic diabetic foot pathologies such as infection, diabetic foot ulcer and neuropathic osteoarthropathy is called diabetic foot syndrome.

The presence of several characteristic diabetic foot pathologies such as infection, diabetic foot ulcer and neuropathic osteoarthropathy is called diabetic foot syndrome.


Pathophysiology

  • Diabetic neuropathy (peripheral & autonomic)
  • Mechanical disruption
  • Vascular insufficiency (Diabetic microangiopathy)
  • Impaired tissue healing

Presentation

  • Pain, as well as reduced sensations of foot
  • Ulceration
  • Absence of peripheral pulses
    • Notably posterior tibial and dorsalis pedis artery
  • Systemic (late) symptoms:
    • Ketoacidosis
    • Septicaemia
    • Myocardial infarction

Wagner-Meggitt Classification of Diabetic foot:

Grade 0Foot symptoms like pain, only
Grade 1Superficial ulcers
Grade 2Deep ulcers
Grade 3Ulcer with bone involvement
Grade 4Forefoot gangrene
Grade 5Full foot gangrene

Diagnosis

Clinical examination:

Blood panel:

  • RBS (Random blood sugar)
  • Blood urea & serum creatinine
  • TLC
  • Total Hb
  • HbA1c estimation
  • Serum albumin
    • Nutritional status

Imaging:

  • MRI (M/sensitive)
  • Doppler/Duplex scan
  • MR angiography

Management

Medical management:

Treat underlying cause
  • Broad-spectrum antibiotics
  • Control of blood sugar
  • Blood transfusion (if required)
  • High-protein diet (if ↓ serum albumin)

Surgical management:

Foot can be saved only if good blood supply is present
  • Debridement of ulcer
  • Irrigation of ulcer
  • Cleaning of ulcer

Care of feet:

  • Avoid injuries
  • Feet kept clean & dry
  • Microcellular rubber (MCR) footwears

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