Enterohaemorragic E. coli infection and HUS

Enterohaemorragic E. coli infection and haemolytic–uraemic syndrome. HUS occurs at the 6th day after diarrhoea in EHEC enteritis; with an overall incidence of 6–9% and in STEC-O104:H4’s outbreak of 30%. On the other hand, 70% of HUS cases occur in the context of EHEC enteritis. HUS triad comprises microangiopathic haemolytic anaemia, thrombocytopenia and AKI. Patients who develop AKI, 50% will require RRT and 5–10% will remain with renal sequelae. 5–7% of patients with HUS do not survive. EHEC: enterohaemorragic E. coli; HUS: haemolytic–uraemic syndrome; RRT: renal replacement therapies; STEC: Shiga-like toxin producing E. coli; AKI: acute kidney injury.

Enterohaemorragic E. coli infection and haemolytic–uraemic syndrome. HUS

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