Microsoft PowerPoint – biochi_4364_Figure 2

Hypothetical model showing the sequential events leading to the inflammatory demyelination in CALD. The inset images are characteristic MRI features of a boy afflicted by CALD. The left panel shows a T2-weighted image with a symmetric and confluent demyelinating lesion within the parieto-occipital lobes. The right panel shows a T1-weighted image post gadolinium administration. Gadolinium enhancement indicates active inflammation and disruption of the blood brain barrier. | Berger, J., Forss-Petter, S., & Eichler, F. S. (2014). Pathophysiology of X-linked adrenoleukodystrophy. Biochimie, 98(100), 135–142. https://doi.org/10.1016/j.biochi.2013.11.023

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