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Pathogenesis of FECD. Genetic and environmental factors lead to corneal endothelial cell loss, resulting in corneal edema and blurring of vision. Some characteristic histological findings are endothelial cell morphological changes, thickened Descemet’s membrane, and guttae formation. | Elhalis, H., Azizi, B., & Jurkunas, U. V. (2010). Fuchs endothelial corneal dystrophy. The ocular surface, 8(4), 173–184. https://doi.org/10.1016/s1542-0124(12)70232-x