Spina bifida

Spina bifida is a congenital disorder characterized by failed closure (primary neurulation) or formation (secondary neurulation) of the neural tube, resulting in abnormalities of the vertebral column and/or spinal cord. This PrimeView discusses the risk factors for spina bifida, including myelomeningocele — the most common and disabling form. | Spina bifida. Nat Rev Dis Prim [Internet]. 2015 Apr 30;1:15051. Available from: http://dx.doi.org/10.1038/nrdp.2015.51