Slit-lamp photographs: (A–D) Case S-2. (A) Filthy soft contact lens case, (B) ring ulcer at first visit, (C) disciform infiltrations with keratoprecipitates at 2 months after referral, and (D) corneal scar and mature cataract at 12 months after referral. (E–G) Case S-4. (E) Superficial punctate keratopathy at first visit, (F) ring infiltration with keratoprecipitates at 3 months after referral, and (G) corneal scar at 2 years after referral. (H and I) Case M-5. (H) Keratoneuritis and ciliary injection at first visit, and (I) clear cornea at 3 weeks after referral. | Shimmura-Tomita, M., Takano, H., Kinoshita, N., Toyoda, F., Tanaka, Y., Takagi, R., Kobayashi, M., & Kakehashi, A. (2018). Risk factors and clinical signs of severe Acanthamoeba keratitis. Clinical ophthalmology (Auckland, N.Z.), 12, 2567–2573. https://doi.org/10.2147/OPTH.S179360

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