Contents
Rebound nasal congestion brought on by extended use of topical decongestants and certain oral medications that vasoconstrict the blood vessels in the lining of the nose.
- Topical decongestants:
- Oxymetazoline
- Phenylephrine
- Xylometazoline
- Naphazoline nasal sprays
- Oral medications:
- Sympathomimetic amines
- Various 2-imidazolines

Clinical features
- Nasal congestion without rhinorrhea, postnasal drip, or sneezing
- Following several days of decongestant use (typically after 5–7 days of use)
- Turbinate hypertrophy: Swelling of the nasal passages caused by rebound congestion may eventually result in permanent turbinate hypertrophy, which may block nasal breathing until surgically removed.
Management
Withdrawal of the offending nasal spray or oral medication.
- Cold turkey approach: M/effective treatment method as it directly removes the cause of the condition
- Gradual weaning approach: Helps preserve normal nasal airflow during the withdrawal process