Inherited disorder of primary (sensory) cilia characterized by cystic expansion of the kidneys producing progressive kidney enlargement and renal insufficiency, in addition to various extrarenal manifestations.
Tag: Ciliopathy
Genetically heterogeneous group of disorders that are caused by mutations in genes with products that localize to the cilium–centrosome complex. Physiology Cilia structure: Cilia are hair-like organelles projecting from the apical surface of polarized cells. Whether in single-celled organisms or in mammals, the form and function of cilia have been conserved over the course of…