Cornea verticillata

Cornea verticillata

Cornea verticillata, also called vortex keratopathy, whorl keratopathy, or Fleischer vortex is a whorl-like pattern of golden brown or gray opacities in the cornea.


M/C causes:

  • Amiodarone
  • Fabry disease

Pharmacologic associations:

  • Chloroquine and Hydroxychloroquine
  • Indomethacin
  • Phenothiazines

Non-pharmacologic aetiologies:

  • Multiple myeloma (MM)
  • Neurotrophic keratitis
  • Lisch corneal dystrophy
  • Epidemic keratoconjunctivitis
  • Iron deposition (i.e., after radial keratotomy)
  • Stromal deposition (gold, silver, antacid, retinoid depositions)

Clinical features

  • Fine golden-brown or gray opacities in the basal epithelium that branch out from a central whorl, usually across the inferior cornea (no visual disturbance)


No recommended treatment

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